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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESCO2
All Species:
0
Human Site:
T254
Identified Species:
0
UniProt:
Q56NI9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56NI9
NP_001017420.1
601
68307
T254
E
T
V
S
E
K
K
T
F
A
T
R
Q
V
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543224
598
67974
K257
E
T
A
R
Q
V
P
K
S
L
L
L
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIB9
592
67255
V264
Q
I
P
K
S
L
L
V
D
E
K
S
S
V
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508920
682
76075
A216
F
F
A
T
R
K
K
A
H
P
V
P
R
K
C
Chicken
Gallus gallus
XP_420012
679
73766
R311
S
T
S
V
P
Q
K
R
E
N
N
N
G
G
N
Frog
Xenopus laevis
NP_001089603
640
69941
K267
L
P
P
H
S
A
F
K
G
V
F
C
V
A
E
Zebra Danio
Brachydanio rerio
Q5SPR8
609
68341
E260
E
V
S
H
D
K
R
E
S
T
Q
A
P
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791750
838
93461
Q321
K
K
V
H
S
K
E
Q
S
T
K
T
K
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146746
323
35496
Q28
G
D
G
E
G
N
G
Q
G
N
V
G
A
A
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
74.2
N.A.
69
N.A.
N.A.
45.8
37.4
36.7
37.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
84.1
N.A.
80
N.A.
N.A.
60.4
53.4
51.5
53.5
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
13.3
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
13.3
N.A.
N.A.
26.6
20
0
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
21.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
0
12
0
12
0
12
0
12
12
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% C
% Asp:
0
12
0
0
12
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
34
0
0
12
12
0
12
12
12
12
0
0
12
0
23
% E
% Phe:
12
12
0
0
0
0
12
0
12
0
12
0
0
0
0
% F
% Gly:
12
0
12
0
12
0
12
0
23
0
0
12
12
12
0
% G
% His:
0
0
0
34
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
12
0
45
34
23
0
0
23
0
12
23
12
% K
% Leu:
12
0
0
0
0
12
12
0
0
12
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
23
12
12
0
12
12
% N
% Pro:
0
12
23
0
12
0
12
0
0
12
0
12
12
0
12
% P
% Gln:
12
0
0
0
12
12
0
23
0
0
12
0
12
0
12
% Q
% Arg:
0
0
0
12
12
0
12
12
0
0
0
12
12
0
0
% R
% Ser:
12
0
23
12
34
0
0
0
34
0
0
12
12
0
12
% S
% Thr:
0
34
0
12
0
0
0
12
0
23
12
12
0
0
12
% T
% Val:
0
12
23
12
0
12
0
12
0
12
23
0
12
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _